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KMID : 0614619950270050595
Korean Journal of Gastroenterology
1995 Volume.27 No. 5 p.595 ~ p.601
Mesenteric Venous Thrombosis, a Rare and Fatal Complication of Hepatocellular Carcinoma
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Abstract
Mesenteric venous thrombosis (MVT) is a rare but distinct form of intestinal ischemia. Most patients with acute MVT usually present symptoms of acute abdominal pain, ileus, ascites, and mucoid or bloody diarrhea, and have rapidly deteriorating
clinical
courses. Portal vein thrombosis (PVT) can be frequently seen in patients with hepatocellular carcinoma (HCC) hut MVT has rarely been reported. Because of rapid and complete compromise of venous drainage from the involved bowel and the rare chance
of
adequate collateral formation, MVT occurrence in patients with HCC could be one of fatal complications resulting in rapid deterioration and early death. We observed four cases of MVT in HCC, and analysed clinical data. Most of our patients had
severe
abdominal pain, nausea, vomiting, bloody diarrhea, uncontrolled ascites, and severe bowel edema. MVT could be verified by doppler ultrasonography, abdominal computerized tomography, and selective angiography. In spite of intensive medical care,
they all
died within 1~4 months, due to intractable gastrointestinal bleeding, hepatorenal syndrome, or sepsis. We present four cases of MVT in HCC patients with a review of the related literature. (Korean J Gastroenterol 1995; 27: 595-601)
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